U.S. Spect products | Renal

Technescan MAG3™

(kit for the preparation of technetium Tc 99m mertiatide)

This information is intended for U.S. healthcare professionals only.

Product information

Technescan MAG3™ (kit for the preparation of technetium Tc 99m mertiatide)

The preferred choice for renal scintigraphy.1

Technescan MAG3 imaging agent delivers both the quantitative and qualitative information you need to help provide a confident diagnosis for patients with a wide variety of renal disorders.

Image quality aids in patient diagnosis

  • High extraction fraction –– more than twice that of Tc 99m DTPA2
  • Provides high kidney-to-background ratio

Single 30-minute procedure delivers renal flow and function results3,4

  • Allows measurement of overall renal function and visualization of renal blood flow
  • Evaluates effective renal plasma flow (ERPF) which is a highly sensitive indicator of renal function5
  • Renal uptake and rapid tubular secretion promotes assessment of renal function

Delivers information you need to help you feel confident about your diagnosis

  • Provides renal function and flow data for assessment of a wide variety of renal disorders such as renal obstruction, renal transplant, and renovascular hypertension
  • Allows assessment of patients with poor renal function2
  • Provides assessment of kidney function in pediatric patients 30 days and older

Indication & Usage

Technescan MAG3™ (kit for the preparation of technetium Tc 99m mertiatide) is a renal imaging agent for use in the diagnosis of congenital and acquired abnormalities, renal failure, urinary tract obstruction, and calculi in adults and pediatric patients.  It is a diagnostic aid in providing renal function, split function, renal angiograms, and renogram curves for whole kidney and renal cortex.

Important risk information

Warnings and precautions

  • The contents of this kit are not radioactive. However, after sodium pertechnetate Tc 99m is added, adequate shielding of the final preparation must be maintained.
  • Contents of the reaction vial are intended only for use in the preparation of technetium Tc 99m mertiatide and are NOT to be administered directly to the patient.
  • To help reduce the radiation dose to the bladder, as well as other target organs, the patient should increase his or her fluid intake (unless medically contraindicated) and void as often as possible after the injection of technetium Tc 99m mertiatide for six hours after the imaging procedure.
  • Technetium Tc 99m mertiatide should not be used more than six hours after preparation.
  • It is essential that the user follow the directions carefully and use aseptic procedures normally employed in making additions and withdrawals from sterile, nonpyrogenic containers during the addition of pertechnetate solution and the withdrawal of doses for patient administration.
  • The technetium Tc 99m labeling reactions involved in preparing Technescan MAG3 depend on maintaining the stannous ion in the reduced state. Any oxidant present in the sodium pertechnetate Tc 99m may adversely affect the quality of the radiopharmaceutical. Therefore, sodium pertechnetate Tc 99m containing oxidants should not be employed.
  • Care should be taken to insure minimum radiation exposure to the patient and to occupational workers.
  • Radiopharmaceuticals should be used only by physicians who are qualified by specific training in the safe use and handling of radionuclides.

Adverse reactions

  • The following adverse reactions have been reported: nausea, vomiting, wheezing, dyspnea, itching, rash, tachycardia, hypertension, shaking chills, fever, and seizure.

Use in specific populations

  • Safety and effectiveness in pediatric patients under the age of 30 days have not been established.
  • Breast feeding: Should be temporarily discontinued because Technetium Tc 99m is excreted in human milk during lactation.

Frequently asked questions

The reconstituted vial must be used within six (6) hours of preparation and should be stored at room temperature (15° to 30° C).

Technescan MAG3 can be ordered through your local Sales Representative, or our Customer Service Department at 888.744.1414, option 1 then option 2. Orders are accepted Monday – Friday, 7:00 am to 5:00 pm. CST.

Call Curium Pharmacovigilance / Product Monitoring Department at 866.789.2211

How is this product supplied




Kit: 12 months post manufacture
Reconstituted vial: 6 hours from time of preparation

Storage conditions

Kit: Controlled room temperature 20° to 25°C (68° to 77°F); protect from the light
Reconstituted vial: Stored at room temperature 15° to 30°C until use

Order information

Description Qty Unit Size Order # NDC
Technescan MAG3 kit, 5 vial 1 Kit N096B0 69945-096-20


1AMR/Arlington Medical Resources, Inc., The U.S. Imaging Market Guide, Jul–Dec 2010.

2Taylor A, Nally JV. Clinical Applications of Renal Scintigraphy. AJR 1995; 164: 31-41.

3 Taylor A, Blaufox MD, Dubovsky EV, Fine EJ, Fomei E, et al. Society of Nuclear Medicine procedure guideline for diagnosis of renovascular hypertension 3.0. Procedure guidelines, Policy and Practice, http://interactive.snm.org/docs/pg_ch16_0403.pdf, 2003.

4 Dubovsky E, Russell C, et al. Report of the Radionuclides in Nephrourology Committee for Evaluation of Transplanted Kidney. Seminars in Nuclear Medicine 1999; 29: 175-188.

5 Wellman HN, Milgrom M. Assessment of Renal Transplant Patients with Tc-99m MAG3: Case Reports and review. Dialysis & Transplantation 1992, Vol. 21(11), pp. 720-736.

Product contact information

Maryland Heights