Posted on 24th March 2020
Sr. Radiochemist / Head of Chemistry
Curium is the world’s largest nuclear medicine company with more than a century of industry experience. We develop, manufacture and distribute world-class radiopharmaceutical products to help patients around the globe. Our proven heritage combined with a pioneering approach are the hallmarks to deliver innovation, excellence and unparalleled service.
With manufacturing facilities across Europe and the United States, Curium delivers SPECT, PET and therapeutic radiopharmaceutical solutions for life-threatening diseases to over 14 million patients annually. The name ‘Curium’ honors the legacy of pioneering radioactive researchers Marie and Pierre Curie, after whom the radioactive element curium was named and emphasizes our focus on nuclear medicine. The tagline ‘Life Forward’ represents our commitment to securing a brighter future for all those we serve: An enhanced quality of care for our patients. A trusted partner to our customers. A supportive employer to our valued team.
Summary of Position
The Sr. Radiochemist / Head of Chemistry, will lead in the management, development, implementation and validation for new radiopharmaceuticals, radiochemicals and isotope production. The position will contribute to the qualification/validation campaign for new radiopharmaceutical implementations in accordance with GMP standards. The position will also contribute to the ongoing process improvement of existing radiochemical processes.
- Leads the Chemistry unit of the Research & Development (R&D) Programs on the Industrialization of new synthesis processes.
- Contributes to the qualification/validation campaign for new radiopharmaceutical implementations in accordance with GMP standards.
- Collaborates with the Engineering Team to design, develop and test production equipment for the radiochemistry process. Oversees and supports the ongoing production of isotopes and/or radiopharmaceuticals.
- Oversees the successful transfer and implementation of technical transfer experiments.
- Works with appropriate personnel to install, qualify and maintain new equipment on-site.
- Oversees the improvement of current cGMP and non GMP processes.
- Ensures the Chemistry Team follows all SOP guidelines for QC (Quality Control) release testing of radiopharmaceutical product, raw material, finished and semi-finished product, environment and facilities.
- Reviews technical documents, procedures and processes, making recommendations for improvements, modifications, updates and changes.
- Ensures the Chemistry Team maintains a clean and safe work environment, performing radiation safety duties in compliance with safety and pharmaceutical regulations.Maintains accurate radiopharmaceutical production and test/validation results.
- Participates in the development and writing of Standard Operating Procedures (SOPs) for the production process. Coordinates and manages the team’s activities to align with objectives.
- Responsible for the ongoing training and development of the team.
- Performs other duties as assigned.
- Minimum of 7 years of experience in radiopharmaceutical synthesis and/or isotope production, radiopharmaceutical development and labeling techniques is required.
- Masters’ Degree in a Chemistry discipline or a related field is required. PhD is preferred.
- Requires expertise in analytical methods and equipment (ICPMS, GC, radiometric measurements, TLC).
- Requires expertise with laboratory procedures and radiochemistry techniques (separation techniques – SPE).
- Must be able to comprehend, analyze and interpret common scientific and technical journals, financial reports and legal documents
- Proven leadership experience working within and across teams building a collaborative culture.
- Possess a familiarity with cyclotron solid targets, process, dissolution and separation of radioisotopes.
- Familiarity with radiation protection and safe handling of radioactive materials.
- Must have knowledge of cGMP, FDA regulations.
- Requires excellent communication, presentation, organization, analytical and computer/pc skills (including Microsoft Office and other related software). May be required to present information of a technical nature to senior management, boards of directors, public groups, regulatory and government agencies and others.
- Must be able to travel up to 10% of the time, which may require overnight travel.
- Willingness to work in a plant producing radioactive materials and requiring all employees to participate in safety programs designed to minimize potential and/or actual exposure levels.
- Standard office environment, coupled with working in radiopharmaceutical manufacturing and laboratory environments. Occupational exposure to radiation.
- Must be willing to wear a variety of personal protective equipment.
- Willingness to work in a team based environment.
- Close attention to detail required.
- May be required to sit or stand for long periods of time while performing duties.
- Must be able to work outside of regular work hours.
- Responsibilities also include Light to moderate physical exertion, including occasional standing, bending, reaching and occasional lifting and carrying of light to moderate loads (of up to 55 pounds) as well as the ability to walk, stoop, push, pull, and climb stairs without accommodation.
- Must possess good hand-eye coordination.
The above statements are intended to describe the general nature and level of work being performed by employees assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of employees assigned to this position.
Equal Opportunity Employer
Curium is an equal opportunity employer and believes everyone deserves respect, dignity and equality. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
Posted on 27th February 2020